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This Concept Map, created with IHMC CmapTools, has information related to: Red Cell Fragmentation Syndromes, Thrombotic Thrombocytopenic Purpura (TTP) characterized by Apparent thrombocytopenia, Removes anti-ADAMTS13 antibodies which Gives ideal treatment when taken together, anti-ADAMTS13 antibodies treated by Antibody supression, Mechanical Heart Valves cause Mechanical shearing of RBCs, Inherited caused by Recesive mutation, Mechanical shearing of RBCs resulting in Hemolytic anemia, Fragmentation of red cells seen as Schistoctes on blood smear, Antibody supression which Prevents antibody attach on ADAMTS13, Multimeric platelet-binding protein which is Cleaved by ADAMTS13, Prosthetic arteries cause Mechanical shearing of RBCs, Fresh frozen Plasma infusion which Supplies healthy ADAMTS13, Cleaved by ADAMTS13 in Normal case, Cleaved by ADAMTS13 except in ADAMTS13 Deficiency, Thrombotic Thrombocytopenic Purpura (TTP) can be Inherited, anti-ADAMTS13 antibodies treated by Plasmapheresis, Thrombotic Thrombocytopenic Purpura (TTP) forms Fibrin mesh, Platelet aggregation forms Fibrin mesh, Fibrin mesh causes Fragmentation of red cells, Aggregation of vWF and platelets results in Thrombotic Thrombocytopenic Purpura (TTP), Apparent Thrombocytopenia but has Normal ADAMTS13 levels